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Xiaoping Chen Selected Research

Colorectal Neoplasms (Colorectal Cancer)

4/2023Effects of prebiotic supplement on gut microbiota, drug bioavailability, and adverse effects in patients with colorectal cancer at different primary tumor locations receiving chemotherapy: study protocol for a randomized clinical trial.
7/2021Prognostic and immunological roles of Fc fragment of IgG binding protein in colorectal cancer.
1/2021Identification of Cysteine Protease Inhibitor CST2 as a Potential Biomarker for Colorectal Cancer.
1/2021Targeting NUFIP1 Suppresses Growth and Induces Senescence of Colorectal Cancer Cells.
1/2020Transcription Factor EBF1 Over-Expression Suppresses Tumor Growth in vivo and in vitro via Modulation of the PNO1/p53 Pathway in Colorectal Cancer.
2/2019High PLK4 expression promotes tumor progression and induces epithelial‑mesenchymal transition by regulating the Wnt/β‑catenin signaling pathway in colorectal cancer.
1/2017Preoperative plasma fibrinogen, but not D-dimer might represent a prognostic factor in non-metastatic colorectal cancer: A prospective cohort study.
3/2016Novel role of STRAP in progression and metastasis of colorectal cancer through Wnt/β-catenin signaling.
3/2016Smad4 sensitizes colorectal cancer to 5-fluorouracil through cell cycle arrest by inhibiting the PI3K/Akt/CDC2/survivin cascade.
11/2013Targeting the ERK pathway reduces liver metastasis of Smad4-inactivated colorectal cancer.
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Xiaoping Chen Research Topics

Disease

119Neoplasms (Cancer)
05/2024 - 09/2002
63Hepatocellular Carcinoma (Hepatoma)
03/2024 - 01/2003
35Neoplasm Metastasis (Metastasis)
02/2024 - 09/2002
30Hypertension (High Blood Pressure)
04/2024 - 06/2009
26Inflammation (Inflammations)
05/2024 - 11/2008
20Infections
05/2024 - 10/2008
18Carcinogenesis
04/2023 - 08/2002
17Malaria
04/2023 - 07/2003
15Lung Neoplasms (Lung Cancer)
01/2023 - 08/2006
13Essential Hypertension
04/2024 - 08/2009
13Colorectal Neoplasms (Colorectal Cancer)
04/2023 - 07/2012
12Type 2 Diabetes Mellitus (MODY)
01/2023 - 09/2014
12Hypoxia (Hypoxemia)
01/2023 - 08/2010
11Liver Neoplasms (Liver Cancer)
02/2024 - 01/2004
10Muscular Atrophy (Muscle Atrophy)
04/2024 - 01/2007
10Cardiovascular Diseases (Cardiovascular Disease)
04/2023 - 06/2009
9Carcinoma (Carcinomatosis)
01/2021 - 09/2002
8Glioma (Gliomas)
05/2024 - 03/2013
8Insulin Resistance
02/2024 - 01/2007
8Fibrosis (Cirrhosis)
01/2024 - 01/2004
8Coronary Artery Disease (Coronary Atherosclerosis)
12/2023 - 01/2018
8COVID-19
04/2023 - 09/2020
7Chronic Hepatitis B
09/2019 - 02/2014
6Liver Cirrhosis (Hepatic Cirrhosis)
12/2023 - 01/2015
6Diabetes Mellitus
01/2022 - 01/2012
6Atherosclerosis
01/2022 - 10/2012
6Neurodegenerative Diseases (Neurodegenerative Disease)
10/2018 - 02/2010
5Cholangiocarcinoma
05/2024 - 01/2005
5Ovarian Neoplasms (Ovarian Cancer)
01/2023 - 03/2020
5Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy)
01/2023 - 02/2020
5Ischemia
11/2022 - 12/2012
5Hemorrhage
05/2022 - 02/2007
5Hypertrophy
01/2021 - 10/2009
5Body Weight (Weight, Body)
01/2021 - 05/2004
4Breast Neoplasms (Breast Cancer)
05/2024 - 04/2007
4Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
04/2024 - 01/2019
4Hypersensitivity (Allergy)
08/2023 - 12/2007
4Portal Hypertension
01/2023 - 01/2004
4Idiopathic Pulmonary Fibrosis
12/2022 - 01/2019
4Necrosis
11/2022 - 04/2010
4Adenoma (Adenomas)
10/2022 - 09/2013
4Pain (Aches)
05/2022 - 01/2018
4Cicatrix (Scar)
03/2022 - 10/2009
4Reperfusion Injury
11/2021 - 08/2009
4Orthostatic Hypotension (Postural Hypotension)
03/2021 - 11/2014
4Coronary Disease (Coronary Heart Disease)
10/2020 - 04/2002

Drug/Important Bio-Agent (IBA)

42Proteins (Proteins, Gene)FDA Link
05/2024 - 04/2002
25Biomarkers (Surrogate Marker)IBA
05/2024 - 05/2014
20Glucose (Dextrose)FDA LinkGeneric
02/2024 - 09/2004
17Messenger RNA (mRNA)IBA
01/2023 - 01/2004
15MicroRNAs (MicroRNA)IBA
01/2023 - 05/2013
14Long Noncoding RNAIBA
01/2023 - 09/2017
11RNA (Ribonucleic Acid)IBA
01/2024 - 01/2020
10Antihypertensive Agents (Antihypertensives)IBA
05/2024 - 10/2011
10Transcription Factors (Transcription Factor)IBA
05/2024 - 01/2009
10LipidsIBA
01/2024 - 08/2010
10Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
09/2023 - 09/2002
9CytokinesIBA
05/2024 - 10/2008
8Phosphotransferases (Kinase)IBA
09/2022 - 01/2018
7Triglycerides (Triacylglycerol)IBA
02/2024 - 01/2012
7Indicators and Reagents (Reagents)IBA
01/2023 - 05/2004
7Immune Checkpoint InhibitorsIBA
01/2023 - 09/2020
6Transforming Growth Factors (Transforming Growth Factor)IBA
09/2022 - 11/2013
6AntibodiesIBA
01/2022 - 08/2010
6Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2022 - 12/2003
6EnzymesIBA
01/2019 - 10/2009
5Hormones (Hormone)IBA
05/2024 - 01/2020
5TabletsIBA
04/2024 - 12/2018
5Circular RNAIBA
03/2024 - 10/2016
5Amlodipine (Norvasc)FDA LinkGeneric
02/2024 - 10/2009
5UbiquitinIBA
07/2023 - 01/2007
5Antiviral Agents (Antivirals)IBA
04/2023 - 03/2015
5Insulin (Novolin)FDA Link
01/2022 - 01/2021
5CholesterolIBA
05/2021 - 02/2014
5AflatoxinsIBA
12/2020 - 02/2008
4Sorafenib (BAY 43-9006)FDA Link
03/2024 - 02/2016
4alpha-Fetoproteins (alpha-Fetoprotein)IBA
02/2024 - 10/2020
4Reactive Oxygen Species (Oxygen Radicals)IBA
01/2024 - 01/2019
4DNA (Deoxyribonucleic Acid)IBA
02/2023 - 02/2010
46-methyladenineIBA
01/2023 - 03/2022
4AntigensIBA
01/2023 - 04/2017
4CalciumIBA
01/2023 - 05/2004
4omega-Chloroacetophenone (Mace)IBA
10/2022 - 05/2014
4Uric Acid (Urate)IBA
06/2022 - 10/2018
4Therapeutic UsesIBA
06/2022 - 01/2018
4PlatinumIBA
01/2022 - 09/2017
4InterferonsIBA
01/2022 - 03/2018
4C-Reactive ProteinIBA
01/2022 - 01/2017
4AlbuminsIBA
12/2021 - 01/2018
4hydroxide ionIBA
03/2021 - 11/2014
4Hepatitis B Surface Antigens (HBsAg)FDA Link
09/2019 - 01/2005

Therapy/Procedure

67Therapeutics
05/2024 - 03/2007
20Immunotherapy
04/2024 - 01/2016
14Drug Therapy (Chemotherapy)
04/2024 - 01/2003
12Hepatectomy
01/2023 - 02/2014
6Splenectomy
01/2021 - 08/2002
5Denervation
12/2022 - 01/2007
5Chinese Traditional Medicine (Traditional Chinese Medicine)
01/2021 - 01/2018
4Bed Rest (Bedrest)
04/2024 - 01/2007
4Radiotherapy
11/2022 - 01/2019